Tiny Earth Chemistry Hub

The Tiny Earth Chemistry Hub (TECH) brings student-based discovery to new heights. TECH was established in 2018 at the Wisconsin Institute for Discovery as part of the “Science and Discovery” core of Tiny Earth. Multidisciplinary approaches allow TECH to go beyond what can be accomplished in one semester and move the network closer to discovering the next antibiotic.

TECH’s growing isolate collection includes nearly 3,000 strains from over 20 institutions. The diversity of soil environments, culture conditions, and isolates is a rich asset to TECH and its mission of antibiotic discovery. These isolates are evaluated and prioritized based on activity profiles, genomic, and metabolomic data and some are scaled up for structural elucidation.

The Tiny Earth Chemistry Hub always welcomes collaborators in its quest to discover novel antibiotic compounds. Get in touch today!

Quick Documents

Material Transfer Agreement (MTA)

Submit Isolates to TECH

Database

The Tiny Earth Database holds records of soil samples, culture conditions, and inhibitory bacteria that have been isolated from all over the world and is critical for discovering new antibiotics.

It standardizes record keeping and allows information to be shared with the entire Tiny Earth network, including the Tiny Earth Chemistry Hub. The public-facing side of the database is used for genomic research, classroom studies, and more as students search for discovery patterns and novel compounds.

The Tiny Earth Chemistry Hub uses the Database for accurate record keeping, comparisons to previous activity and results, and will be used to share information with users in the future.

Access the Tiny Earth Public Database
Download the Database Tutorial

Tiny Earth Database Webinar

Meet the TECH Team

Jo Handelsman
Jo HandelsmanFounder
Sarah Miller
Sarah MillerExecutive Director
Martel DenHartog
Martel DenHartogChemistry Hub Manager
Julia DuncanPostdoctoral Researcher
Julia Nepper
Julia NepperPostdoctoral Researcher
Trang Tran
Trang TranOutreach Specialist
Marc Chevrette
Marc ChevretteGenomics Director
Grace Pausma
Grace PausmaResearch Intern

Antibiotic Pipeline

Instructors

Worldwide network of instructors teach evidence-based hands-on science.

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Instructors Worldwide
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Trained Yearly
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Historically Excluded Groups

Students

Students study microbes from local soils with interactive research.

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Students per Year
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Institutions

Database

Pathogen-inhibiting isolates are recorded in the global Tiny Earth Database and shared.

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Total lsolates
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Isolates from Outside the U.S.

Chemistry Hub

Students share samples with the Chemistry Hub scientists for genomic and metabolomic analysis.

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Contributing Institutions
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Isolates in the Collection
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Complete Genome Sequences
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Metabolomes Analyzed
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High Priority Isolates

Antibiotic Structures

Identifying antibiotic compounds to combat the resistance crisis.

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Antibiotic Structures Identified